Laboratory for Control, Learning, and Systems Biology

controllability

2018
  1. Y. Zarai, M. Margaliot, E.D. Sontag, T. Tuller, "Controllability analysis and control synthesis for the ribosome flow model", IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol. 15, pp. 1351-1364, 2018. pdf
    Abstract

    The ribosomal density along the coding region of the mRNA molecule affects various fundamental intracellular phenomena including: protein production rates, organismal fitness, ribosomal drop off, and co-translational protein folding. Thus, regulating translation in order to obtain a desired ribosomal profile along the mRNA molecule is an important biological problem. This paper studies this problem formulated in the context of the ribosome flow model (RFM) in which one views the transition rates between site as controls.

2001
  1. A. C. Antoulas, E. D. Sontag, Y. Yamamoto, "Controllability and Observability", In Wiley Encyclopedia of Electrical and Electronics Engineering, pp. 264-281, 2001. wwwdoipdf
1999
  1. E.D. Sontag, Y. Qiao, "Further results on controllability of recurrent neural networks", Systems Control Lett., vol. 36, no. 2, pp. 121–129, 1999. pdf
    Abstract

    This paper studies controllability properties of recurrent neural networks. The new contributions are: (1) an extension of the result in "Complete controllability of continuous-time recurrent neural networks" to a slightly different model, where inputs appear in an affine form, (2) a formulation and proof of a necessary and sufficient condition, in terms of local-local controllability, and (3) a complete analysis of the 2-dimensional case for which the hypotheses made in previous work do not apply.

1998
  1. E.D. Sontag, F.R. Wirth, "Remarks on universal nonsingular controls for discrete-time systems", Systems Control Lett., vol. 33, no. 2, pp. 81–88, 1998. doipdf
    Abstract

    For analytic discrete-time systems, it is shown that uniform forward accessibility implies the generic existence of universal nonsingular control sequences. A particular application is given by considering forward accessible systems on compact manifolds. For general systems, it is proved that the complement of the set of universal sequences of infinite length is of the first category. For classes of systems satisfying a descending chain condition, and in particular for systems defined by polynomial dynamics, forward accessibility implies uniform forward accessibility.

  2. E.D. Sontag, "A general approach to path planning for systems without drift", In Essays on mathematical robotics (Minneapolis, MN, 1993), pp. 151–168, 1998. pdf
    Abstract

    This paper proposes a generally applicable technique for the control of analytic systems with no drift. The method is based on the generation of "nonsingular loops" that allow linearized controllability. One can then implement Newton and/or gradient searches in the search for a control. A general convergence theorem is proved.

1995
  1. E.D. Sontag, "Control of systems without drift via generic loops", IEEE Trans. Automat. Control, vol. 40, no. 7, pp. 1210–1219, 1995. pdf
    Abstract

    This paper proposes a simple numerical technique for the steering of arbitrary analytic systems with no drift. It is based on the generation of "nonsingular loops" which allow linearized controllability along suitable trajetories. Once such loops are available, it is possible to employ standard Newton or steepest descent methods, as classically done in numerical control. The theoretical justification of the approach relies on recent results establishing the genericity of nonsingular controls, as well as a simple convergence lemma.

  2. E.D. Sontag, "From linear to nonlinear: some complexity comparisons", In Proc.\ IEEE Conf.\ Decision and Control, New Orleans, Dec.\ 1995, IEEE Publications, 1995, pp. 2916–2920, 1995. pdf
    Abstract

    This paper deals with the computational complexity, and in some cases undecidability, of several problems in nonlinear control. The objective is to compare the theoretical difficulty of solving such problems to the corresponding problems for linear systems. In particular, the problem of null-controllability for systems with saturations (of a "neural network" type) is mentioned, as well as problems regarding piecewise linear (hybrid) systems. A comparison of accessibility, which can be checked fairly simply by Lie-algebraic methods, and controllability, which is at least NP-hard for bilinear systems, is carried out. Finally, some remarks are given on analog computation in this context.

1993
  1. F. Albertini, E.D. Sontag, "Discrete-time transitivity and accessibility: analytic systems", SIAM J. Control Optim., vol. 31, no. 6, pp. 1599–1622, 1993. doipdf
    Abstract

    A basic open question for discrete-time nonlinear systems is that of determining when, in analogy with the classical continuous-time "positive form of Chow's Lemma", accessibility follows from transitivity of a natural group action. This paper studies the problem, and establishes the desired implication for analytic systems in several cases: (i) compact state space, (ii) under a Poisson stability condition, and (iii) in a generic sense. In addition, the paper studies accessibility properties of the "control sets" recently introduced in the context of dynamical systems studies. Finally, various examples and counterexamples are provided relating the various Lie algebras introduced in past work.

  2. E.D. Sontag, "Gradient techniques for systems with no drift: A classical idea revisited", In Proc. IEEE Conf. Decision and Control, San Antonio, Dec. 1993, IEEE Publications, 1993, pp. 2706–2711, 1993. pdf
    Abstract

    This paper proposes a technique for the control of analytic systems with no drift. It is based on the generation of "nonsingular loops" which allow linearized controllability. Once such loops are available, it is possible to employ standard Newton or steepest descent methods. The theoretical justification of the approach relies on results on genericity of nonsingular controls as well as a simple convergence lemma.

1992
  1. E.D. Sontag, "Universal nonsingular controls", Systems Control Lett., vol. 19, no. 3, pp. 221–224, 1992. doipdf
    Erratum appeared in SCL 20(1993), p. 77, can be found in same file.
    Abstract

    For analytic systems satisfying the strong accessibility rank condition, generic inputs produce trajectories along which the linearized system is controllable. Applications to the steering of systems without drift are briefly mentioned.

1991
  1. F. Albertini, E.D. Sontag, "Some connections between chaotic dynamical systems and control systems", In Proc.\ European Control Conf.\ \/, Vol 1, Grenoble, July 1991, pp. 58–163, 1991. pdf
    Abstract

    This paper shows how to extend recent results of Colonius and Kliemann, regarding connections between chaos and controllability, from continuous to discrete time. The extension is nontrivial because the results all rely on basic properties of the accessibility Lie algebra which fail to hold in discrete time. Thus, this paper first develops further results in nonlinear accessibility, and then shows how a theorem can be proved, which while analogous to the one given in the work by Colonius and Klieman, also exhibits some important differences. A counterexample is used to show that the theorem given in continuous time cannot be generalized in a straightforward manner.

  2. E.D. Sontag, "Kalman's controllability rank condition: from linear to nonlinear", In Mathematical system theory, pp. 453–462, 1991. pdf
    Abstract

    The notion of controllability was identified by Kalman as one of the central properties determining system behavior. His simple rank condition is ubiquitous in linear systems analysis. This article presents an elementary and expository overview of the generalizations of this test to a condition for testing accessibility of discrete and continuous time nonlinear systems.

1990
  1. E.D. Sontag, "Integrability of certain distributions associated with actions on manifolds and applications to control problems", In Nonlinear controllability and optimal control, pp. 81–131, 1990. pdf
    Abstract

    Results are given on the integrability of certain distributions which arise from smoothly parametrized families of diffeomorphisms acting on manifolds. Applications to control problems and in particular to the problem of sampling are discussed. Pages 42-50 apply the results to the control of continuous time systems; this is an exposition of some of the basic results of the Lie algebraic accessibility theory.

1988
  1. E.D. Sontag, "Controllability is harder to decide than accessibility", SIAM J. Control Optim., vol. 26, no. 5, pp. 1106–1118, 1988. doipdf
    Abstract

    The present article compares the difficulties of deciding controllability and accessibility. These are standard properties of control systems, but complete algebraic characterizations of controllability have proved elusive. We show in particular that for subsystems of bilinear systems, accessibility can be decided in polynomial time, but controllability is NP-hard.

  2. E.D. Sontag, "Some complexity questions regarding controllability", In Proc.\ IEEE Conf.\ Decision and Control, Austin, Dec.\ 1988, pp. 1326–1329, 1988. pdf
    Abstract

    It has been known for a long time that certain controllability properties are more difficult to verify than others. This article makes this fact precise, comparing controllability with accessibility, for a wide class of nonlinear continuous time systems. The original contribution is in formalizing this comparison in the context of computational complexity. (This paper placed here by special request.)

1983
  1. E.D. Sontag, "Remarks on the preservation of various controllability properties under sampling", In Mathematical tools and models for control, systems analysis and signal processing, Vol. 3 (Toulouse/Paris, 1981/1982), pp. 623–637, 1983. pdf
    Abstract

    This note studies the preservation of controllability (and other properties) under sampling of a nonlinear system. More detailed results are obtained in the cases of analytic systems and of systems with finite dimensional Lie algebras.