BACK TO INDEX

Publications about 'reaction cordinates'
Articles in journal or book chapters
  1. D. Angeli, P. de Leenheer, and E.D. Sontag. Graph-theoretic characterizations of monotonicity of chemical networks in reaction coordinates. J. Mathematical Biology, 61:581-616, 2010. [PDF] Keyword(s): MAPK cascades, reaction networks, fluxes, monotone systems, reaction cordinates, Petri nets, persistence, futile cycles.
    Abstract:
    This paper derives new results for certain classes of chemical reaction networks, linking structural to dynamical properties. In particular, it investigates their monotonicity and convergence without making assumptions on the form of the kinetics (e.g., mass-action) of the dynamical equations involved, and relying only on stoichiometric constraints. The key idea is to find an alternative representation under which the resulting system is monotone. As a simple example, the paper shows that a phosphorylation/dephosphorylation process, which is involved in many signaling cascades, has a global stability property.



BACK TO INDEX




Disclaimer:

This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders.




Last modified: Fri Nov 15 15:28:36 2024
Author: sontag.


This document was translated from BibTEX by bibtex2html