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Publications of Eduardo D. Sontag jointly with R.A. Gatenby
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Articles in journal or book chapters
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L. Liu,
G. Duclos,
B. Sun,
J. Lee,
A. Wu,
Y. Kam,
E.D. Sontag,
H.A. Stone,
J.C. Sturm,
R.A. Gatenby,
and R.H. Austin.
Minimization of thermodynamic costs in cancer cell invasion.
Proc Natl Acad Sci USA,
110:1686-1691,
2013.
[PDF]
Keyword(s): chemotaxis,
cancer,
metastasis.
Abstract:
This paper shows that metastatic breast cancer cells cooperatively invade a 3D collagen matrix while following a glucose gradient. The front cell leadership is dynamic, and invading cells act in a cooperative manner by exchanging leaders in the invading front. |
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